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Pulmonology

PERC Rule

8 inputsPulmonology

Rule out PE in low-probability patients without D-dimer.

PERC Rule calculator

Result

PERC Negative

All 8 absent — PE excluded without D-dimer (low pre-test probability only)

How to use it

  1. 1

    Establish low pre-test probability first. PERC only valid in patients already at low clinical probability (Wells ≤1 or gestalt <15%).

  2. 2

    All 8 criteria must be absent. Any single positive = PERC positive → D-dimer required.

  3. 3

    PERC negative → discharge. Miss rate ~1.4% in validated low-probability populations.

When to use it

Young patient with atypical chest pain and Wells ≤1
PERC negative avoids unnecessary D-dimer and downstream imaging.
Reducing false-positive D-dimers
D-dimer elevates with age, infection, pregnancy — PERC prevents unnecessary workup.
NOT in intermediate/high probability
Do not apply PERC if Wells >1.

A reference for clinicians and students, not medical advice. A score supports a decision; it does not make one. Check every result against the patient in front of you and your local protocol.

At a glance

Specialty
Pulmonology
Inputs
8
Type
Points score

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