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prognia.

Rheumatology

SLEDAI-2K

24 inputsRheumatology

Systemic lupus erythematosus disease activity index.

SLEDAI-2K calculator

Result

0/105

Remission

How to use it

  1. 1

    Only new or worsening features in last 10 days. SLEDAI-2K scores features present at time of assessment regardless of duration (continuous version).

  2. 2

    Neuropsychiatric features weighted highest (8 pts). Seizure, psychosis, CVA, vasculitis — urgent escalation.

  3. 3

    Target score 0–4. LLDAS (Lupus Low Disease Activity State): SLEDAI ≤4, no major organ activity, prednisolone ≤7.5 mg/day.

When to use it

SLE clinic assessment
Serial SLEDAI guides immunosuppression escalation and tapering.
Flare monitoring
Increase of ≥3 points = flare; increase of ≥12 = severe flare.
Belimumab/anifrolumab eligibility
SLEDAI ≥8 (belimumab) or serologically active disease.

A reference for clinicians and students, not medical advice. A score supports a decision; it does not make one. Check every result against the patient in front of you and your local protocol.

At a glance

Specialty
Rheumatology
Inputs
24
Type
Points score

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