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prognia.

Rheumatology

FRAX (Fracture Risk)

10 inputsRheumatology

10-year osteoporotic fracture probability — simplified.

FRAX (Fracture Risk) calculator

Result

~10%10-yr major fx risk

Intermediate — DXA recommended

Simplified estimate. Use FRAX online tool (sheffield.ac.uk/FRAX) for country-specific calculation with BMD.

40 to 90 years

Sex

10 to 60 kg/m²

How to use it

  1. 1

    For accurate FRAX: use the online tool with BMD. FRAX requires country-specific calibration and BMD at femoral neck for precise results.

  2. 2

    10-year major osteoporotic fracture. Hip, spine, humerus, wrist. Separate hip fracture probability also calculated.

  3. 3

    Threshold varies by guideline. UK NOGG: treatment threshold = 10-yr hip risk ≥3% or major risk ≥20% (age-adjusted).

When to use it

Post-menopause or fragility fracture
All women >50 with fragility fracture: DXA + FRAX.
Long-term glucocorticoids
≥5 mg prednisolone for ≥3 months: FRAX underestimates risk (increase by 15%).
DXA result integration
FRAX + T-score −2.5 or worse: treat with bisphosphonate.

A reference for clinicians and students, not medical advice. A score supports a decision; it does not make one. Check every result against the patient in front of you and your local protocol.

At a glance

Specialty
Rheumatology
Inputs
10
Type
Formula

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