A pharmaceutico-experimental evaluation of mridwikadi ghritha in shukravardhana with special reference to spermatogenesis

The concept of Shukravardana (spermatogenesis) dealt under Vajeekarana or Vrishya Chikitsa which is one of the branch of Ayurveda where details of reproductive health are elaborately studied. Vajeekarana treatment revitalize all the Sapta dhatus, increases virility, improve the quality of germinal cells as well as help in treatment of various sexual dysfunctions. Vajeekarana medicines directly act on Shukra dhatu and cause the increase in quantity of semen or it's ejaculation or both. Vajeekarana has a beneficial impact on fertility in addition to improving a person's general health and condition. Goghrita is having well known action in male fertility and spermatogenesis. Acting as ideal lipid-based carrier, it enhances the bioavailability of herbs, carrying nutrients deep into reproductive tissues which helps to treat conditions like Ksheena Shukra (oligospermia) such others and to stimulate spermatogenesis. Mridwikadi ghrita is one such preparations exclusively indicated for only Shukravardana. Classically Mridwikadi Ghrita consists most of all drugs are having vrishya and shukravardaka properties hence this preparation was done to evaluate the impact of formulation in Vajeekarana effect. Currently cases of male infertility as well as female infertility are increasing day by day and cost of treatment is also hiking because of demand. Ayueveda have so many treatments to safety and cost effectively to take care of issues. So, Mridwikadi Ghrita is one such preparation with ingredients which are easily available, cost effective, easy to prepare and with therapeutically effective ingredients has been selected for present study.