Cancers
Maternal and Perinatal Outcomes in Pregnancies Complicated by Predominantly Benign Ovarian Lesions: A Retrospective Case-Control Study of 305 Pregnancies
By Aneta Zamojska, Monika Kopeć, Jan Kotarski and 2 others.
Abstract
Background
Ovarian lesions during pregnancy pose diagnostic and therapeutic challenges for clinicians. This study aimed to describe the characteristics of ovarian lesions diagnosed during pregnancy and compare maternal and perinatal outcomes with those of pregnancies without ovarian pathology.
Methods
A retrospective case–control study was conducted on 305 pregnant women hospitalized at the Department of Obstetrics and Perinatology in Lublin (2011–2020). The study group comprised 105 women with benign ovarian neoplasms (ICD-10 D27; n = 102) or ovarian cancer (C56; n = 3). The reference group comprised 200 women without ovarian pathology, selected by simple random sampling from hospital records. The main outcomes were mode of delivery, duration of pregnancy, birth weight, and APGAR scores. Comorbidities, neonatal diagnoses, and correlations were analyzed as exploratory outcomes using the false discovery rate (FDR) correction.