PloS one
Does receiving red yeast rice prescriptions (LipoCol Forte®) increase the risk of end-stage renal disease or not? A retrospective cohort study
By Chang CC, Lam F, Yeh CC and 3 others.
Abstract
Background
The potential relationship between the consumption of red yeast rice (RYR) and the development of end-stage renal disease (ESRD) remains poorly understood. We aimed to evaluate the risk of ESRD in patients who used RYR.
Methods
Utilizing insurance claim records from 2010 to 2014, we performed a retrospective cohort analysis comparing 67,876 individuals using RYR against a control group of 90,836 lovastatin users (non-RYR group), with follow-up extending through 2019. The incidence of ESRD was analyzed using adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) within Cox proportional hazard models.