JMIR medical informatics
Real-World Applicability of Multiple International Terminology Systems in Oncology: Mapping Study of Clinical Terms for Cancer Diagnosis and Treatment
By Jang B, Park E, Lee S and 8 others.
Abstract
Background
With the rapid expansion of health care data, multiple international standardized terminology systems have been developed and refined to ensure semantic interoperability, which is a crucial factor in facilitating collaborative use.
Objective
This study aimed to evaluate the real-world use and applicability of standardized terminology systems by mapping clinical terms from routine cancer care and to propose guidelines that optimize mapping.
Methods
Clinical terms generated during cancer care at the National Cancer Center Korea were extracted and mapped to multiple target terminology systems: the Korean Standard Classification of Diseases; International Classification of Diseases, 9th Revision, Clinical Modification; Logical Observation Identifiers Names and Codes; RxNorm; Anatomical Therapeutic Chemical classification; and Systematized Nomenclature of Medicine Clinical Terms (SNOMED CT). A multidisciplinary working group of health care information managers, data experts, and oncologists verified the mapping outcomes, calculated the cross-verification discordance rate, and compared the coverage across systems.