The Influence of Neurotic Disorders and…

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Retrospective history revealed recurrent upper respiratory tract infections and bilateral pneumonia in early childhood, followed by increasing anxiety and social withdrawal from peers. The patient was diagnosed with obsessive-compulsive disorder (OCD) at the age of 13, while psychiatric records from 2023 also documented depressive disorders and social phobia. Within the family system, the patient experienced relational trauma, including systematic verbal and psychological abuse by her father. Blood tests performed on 11 June 2025 revealed an elevated antistreptolysin O (ASO) level of 436 IU/mL, which may indicate previous streptococcal exposure but does not confirm active infection, PANDAS/PANS, or a causal relationship with neuropsychiatric symptoms. The available documentation lacked microbiological confirmation of streptococcal infections or evidence substantiating a PANDAS/PANS diagnosis. QEEG brain mapping revealed elevated fast HiBeta activity in the frontal regions under both recording conditions; however, incomplete methodological documentation precluded definitive interpretation of this finding as evidence of persistent cortical overactivity or specific cognitive deficits. Somatic and metabolic findings included morning cortisol of 7.7 µg/dL, dehydroepiandrosterone sulfate (DHEA-SO4) of 163 µg/dL, prolactin of 513.0 mIU/L, and total cholesterol of 138 mg/dL. A previously recorded glycemic value of 45 mg/dL was also noted, although insufficient information was available to confirm reactive hypoglycemia. The patient reported a dichotomous eating pattern characterized by appetite suppression during acute stress, followed by episodes of increased food intake aimed at regulating emotional tension. However, the absence of standardized assessment prevented confirmation of formal binge-eating episodes. Food avoidance and restriction were associated with contamination fears and obsessive-compulsive rituals. The patient also expressed marked body image dissatisfaction and a desire for an extremely thin physique, although no formal diagnosis of body dysmorphic disorder was documented.

The Influence of Neurotic Disorders and Neurobiological Basis on Eating Behavior in a 21-Year-Old Patient: A Case Study-Diagnostic Difficulties: Is It PANDAS/PANS in Relation to an Elevated ASO Level and the Diagnosis of OCD?

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