Brain sciences
Decision-Making Performance and Block-Wise Trajectories in Gambling Disorder and Opioid Use Disorder Using the Iowa Gambling Task
By Gorzelańczyk EJ, Kawala-Sterniuk A, Laskowska E and 2 others.
Abstract
Background/objectives
Decision-making differences have been reported in substance-related and behavioral addictions, but Iowa Gambling Task (IGT) performance patterns may differ. We compared IGT performance in gambling disorder, opioid use disorder (OUD) before and approximately 90 min after methadone dosing, and healthy controls.
Methods
The study enrolled 103 adult men: 33 with gambling disorder, 30 with opioid use disorder (OUD) receiving methadone maintenance, and 40 healthy controls. One control participant discontinued the IGT before completion, leaving 39 complete control outcome records. Between-cohort inference therefore used 39 controls, 33 participants with gambling disorder, and 30 OUD pre-methadone observations; pre-/post-dose inference used 27 complete OUD pairs as repeated measurements.