Antibiotics
Whole-Genome Characterization of Pediatric Urinary E. coli Isolates from a Tertiary Care Pediatric Hospital in Guayaquil, Ecuador: Identification of the High-Risk ST1193 Clone
By Lapo-Calle L, Mejía-Limones I, Avellán-Llaguno RD and 4 others.
Abstract
Background
Escherichia coli is a leading cause of urinary tract infections (UTIs) in children, and increasing antimicrobial resistance complicates empirical treatment. However, genomic information on pediatric urinary E. coli associated with urinary tract infection in Ecuador remains limited.
Objective
This exploratory study analyzed four E. coli isolates obtained from urine samples of pediatric patients at a tertiary hospital in Guayaquil, Ecuador.
Methods
Whole-genome sequencing (WGS) was performed to determine sequence types (STs), serotypes, antimicrobial resistance genes (ARGs) virulence factors (VFs), and phylogenetic relationships.