Medication Complexity and Insomnia Severity in Psychiatric Outpatients: A Moderation Analysis Across Mood and Non-Mood Disorders

Background

Insomnia is common and occurs across psychiatric diagnoses. A prior analysis of this outpatient cohort found that psychotropic medication complexity was associated with insomnia severity, but whether this association is stronger in particular diagnostic groups was not examined. We preregistered a moderation analysis to test whether mood disorder status modifies the association between medication complexity and insomnia, and additionally examined modification by sex and by insomnia domain.