Journal of medical signals and sensors
Comparison of Different Models in Calculation of Tumor Control Probability and Normal Tissue Complication Probability in Breast Cancer Radiotherapy
By Tareq H, Ghorbani M, Deevband MR and 2 others.
Abstract
Background
The aim of this study is to compare tumor control probability (TCP) for the planning target volume (PTV) using Poisson, Niemierko, and Zaider-Minerbo models, and normal tissue complication probability (NTCP) for organs at risk (OARs) using Niemierko, Lyman-Kutcher-Burman (LKB) and relative seriality (RS) models.
Methods
Radiotherapy dosimetry data of sixty breast cancer patients were utilized to calculate TCP and NTCP with various models. Patients underwent planning using a 16-slice CT scanner, delivering 50 Gy in 25 fractions using 6 MV photon beam energy and the Monaco treatment planning system (TPS).