Journal of family & reproductive health
Three and Two Dimensional Saline Infusion Sonohysterography in Diagnosing Uterine Cavity Lesions
By Jafarabadi M, Alizadeh M, Rezayof E and 2 others.
Abstract
Objective
Given the invasive and costly nature of reference diagnostic methods like hysteroscopy , this study aimed to compare the diagnostic accuracy and the dimensional measurement agreement of uterine cavity lesions between two-dimensional saline infusion sonography (2D SIS) and three-dimensional saline infusion sonography (3D SIS) against the gold standard of hysteroscopy and histopathology.
Materials and methods
This cross-sectional study was conducted on 283 female patients who were candidates for hysteroscopy. Prior to surgery, all patients underwent blinded evaluations via 2D SIS and 3D SIS performed by experienced radiologists, and the type, number, location, and size of the lesions were recorded. Subsequently, all patients underwent diagnostic hysteroscopy and tissue sampling for pathological evaluation as the gold standard. Diagnostic performance metrics were calculated, and the dimensional agreement of the lesions between the modalities was statistically evaluated using the Intraclass Correlation Coefficient (ICC) and Bland-Altman analysis.