A genetic profile of hereditary neuropathies in two Southern African cohorts

Introduction

Data on hereditary neuropathies in African populations are sparse. In sub-Saharan Africa, genetic testing for Charcot-Marie-Tooth (CMT)-related neuropathies has been largely limited to PMP22 screening for demyelinating CMT.

Aim

We report the genetic profiles of individuals with hereditary neuropathies enrolled at two centers in Cape Town, South Africa, and Lusaka, Zambia.

Methods