Laryngoscope investigative otolaryngology
Sinonasal Malignancies in Taiwan (2009-2019): Histologic Distribution, Overall Survival, and Temporal Trends in Hematological Versus Nonhematological Tumors
By Wu CH, Lin CH and Liang KL.
Abstract
Background
Sinonasal malignancies are rare and histologically diverse, with limited population-based data from Asia. This study investigated the histologic distribution, factors associated with overall survival (OS), and temporal survival patterns in Taiwan.
Methods
This retrospective population-based study used linked data from the Taiwan National Health Insurance Research Database and Taiwan Cancer Registry. Adults with invasive nasal cavity or paranasal sinus malignancies diagnosed between 2009 and 2019 were included. Factors associated with OS were evaluated using multivariable Cox regression analysis separately for hematological and nonhematological malignancies.