Brain and behavior
Trends and Disparities in Mortality From Pneumonia and Cerebrovascular Disease in the United States (1999-2020)
By Abdullah M, Ali M, Mehmood T and 9 others.
Abstract
Background
Pneumonia is a frequent and often fatal complication of cerebrovascular disease (CVD). Stroke care has improved considerably since the late 1990s, but national trends in deaths involving both conditions and their distribution across demographic and geographic groups have not been described.
Methods
We used the Centers for Disease Control and Prevention Wide Ranging Online Data for Epidemiologic Research (CDC WONDER) Multiple Cause of Death files to identify United States decedents aged 55 years and older who died between 1999 and 2020 with pneumonia (ICD-10 codes J18.0, J18.1, J18.2, J18.8, and J18.9) and CVD (I60-I69), both recorded among the causes of death. Age-adjusted mortality rates (AAMRs) per 100,000 populations were standardized to the 2000 United States population. Joinpoint regression estimated the annual percent change (APC) and average annual percent change (AAPC) overall and by sex, age group, race and ethnicity, urbanization, and census region. A sensitivity analysis of the overall series used a broader pneumonia definition (J12-J18).



