Endocrinology, diabetes & metabolism
Association of Traditional and Emerging Anthropometric Indices With Subclinical Carotid Atherosclerosis in Young Healthy Adults: Insights From the Tehran Lipid and Glucose Study
By Abiri B, Ahmadi AR, Hosseinpanah F and 6 others.
Abstract
Background
Obesity is a major risk factor for cardiovascular disease, but traditional measures like BMI and waist circumference have limitations. New indices, BRI and ABSI, may better reflect fat distribution and cardiovascular risk. This study examined their association with carotid intima-media thickness (cIMT) in young healthy adults.
Methods
In this cross-sectional study within the Tehran Lipid and Glucose Study (TLGS) framework, 572 adults aged 20-40 years underwent anthropometric assessments, biochemical tests and carotid ultrasound for cIMT measurement. Anthropometric indices including BMI, WC, waist-to-height ratio (WHtR), ABSI and BRI were calculated. Associations between these indices and cIMT were analysed using correlation and multivariable linear regression models adjusting for demographic, metabolic and lifestyle factors. Receiver operating characteristic (ROC) curve analyses assessed the predictive ability of the indices for elevated cIMT.