Avicenna journal of phytomedicine
Investigation of the co-administration of flaxseed supplementation with high-intensity interval training, resistance training, or combined training on hematological indices and kidney health in fructose/CCl4-induced NAFLD in rats
By Eghbal Moghanlou A, Eslami Z, Uca M and 2 others.
Abstract
Objective
Types of exercise training and flaxseed are beneficial approaches to improve non-alcoholic fatty liver disease (NAFLD)-induced hematological abnormalities. We aimed to determine which type of exercise training supplemented with flaxseed is more efficient for the improvement of blood and kidney function and hematological parameters in fructose/CCl4-induced NAFLD in rats.
Materials and methods
Forty male Wistar rats were divided randomly into five groups (n= 8): 1) ND (normal diet); 2) high-fat diet (HFD); 3) HFD + resistance training (RT) + Flaxseed; 4) HFD + high-intensity interval training (HIIT) + Flaxseed; and 5) HFD+ RT+ HIIT (CT) + Flaxseed. The interventions administered for 8 weeks once daily after NAFLD induction through CCl4 and fructose (15 weeks), and at the end of the 23rd weeks, hematological and renal indices were analyzed.