BMC nephrology
Longitudinal real-time PCR monitoring of CMV DNAemia and renal function in living-donor kidney transplant recipients with low immunological risk
By Gülteki̇n M, Çakmak E and Bulut A.
Abstract
Objective
This study evaluated the association between CMV DNAemia and renal function during the first 12 months after living-donor kidney transplantation in recipients with low immunological risk and explored differences in CMV DNAemia according to preemptive kidney transplantation status.
Materials and methods
A total of 112 living-donor kidney transplant recipients (mean age, 37.07 ± 14.41 years) were followed for 12 months. CMV DNAemia was monitored using quantitative real-time PCR targeting the UL55 (gB) gene. Longitudinal changes were analysed using Friedman and repeated-measures ANOVA, with the Mann -Whitney U test for between-group creatinine comparisons and the independent-samples t-test for GFR (p < 0.05).