Oral and maxillofacial surgery
The crucial question: does adjuvant radiotherapy confer a survival benefit in pN1 oral squamous cell carcinoma (OSCC)? - A retrospective analysis
By Richter M, Tworek A, Koerdt S and 5 others.
Abstract
Objective
Despite continuous research on the role of adjuvant therapy in the pN1 setting in Oral Squamous Cell Carcinoma (OSCC), clear recommendations for or against its use remain lacking. The objective of this study is to further strengthen the existing evidence base and support informed clinical decision-making.
Materials and methods
This retrospective analysis included all patients with primary pT1-2 pN1 OSCC without extracapsular spread who underwent surgical treatment at the Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin. Survival analyses were performed using Kaplan-Meier methods and Cox regression models for the overall cohort as well as after propensity score matching (PSM).