Immunity, inflammation and disease
Sex-Specific Differences in Symptomatology and Quality of Life Impact of Allergic Rhinitis: A Cross-Sectional Study
By Al-Balas HI, Khamees A, Al Saoud SK and 6 others.
Abstract
Background
Allergic Rhinitis (AR) is a widespread condition that significantly affects the quality of life (QOL) of those affected globally. It contributes to sleep disturbances, fatigue, poor concentration, irritability, and can worsen symptoms in individuals with coexisting asthma. This study examines the impact of AR on QOL in adults, with specific attention to sex differences.
Materials and methods
A cross-sectional online survey using a purpose-designed, non-validated questionnaire was distributed via social media using convenience sampling to 1572 Jordanian adults. The questionnaire collected data on demographics, AR symptoms, triggers, and the impact of AR on mental health, social functioning, and daily life. Data were analyzed using descriptive statistics and Chi-square tests. Multivariable logistic regression was used to adjust for potential confounders, and Benjamini-Hochberg false discovery rate (FDR) correction was applied to account for multiplicity.



