Journal of transplantation
Beginning Kidney Replacement Therapy Before or After Liver Transplantation: Does the Timing of Dialysis Matter? A Cohort Study
By Scherer PF, Ammirati AL, Dos Santos BFC and 9 others.
Abstract
Introduction
Acute kidney injury (AKI) in liver transplant patients is associated with increased morbidity, mortality, and reduced graft survival. However, the impact of the timing of dialysis initiation-before versus after transplantation-remains unclear.
Objectives
To characterize liver transplant recipients with Kidney Disease: Improving Global Outcomes (KDIGO) Stage 3 AKI-requiring dialysis (AKI-D) according to the timing of kidney replacement therapy (KRT) initiation (pre- versus posttransplant) and to evaluate 90-day mortality. Secondary objectives included identifying independent predictors of dialysis dependence and assessing liver graft function at 90 days.