Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
A multicenter study on the risk factors for in-hospital mortality in neonates with severe asphyxia at tertiary hospitals in Henan Province
By Pei WJ, Zhang YH, Li SJ and 21 others.
Abstract
Objectives
To construct a risk prediction model for in-hospital mortality in neonates with severe asphyxia.
Methods
A total of 836 neonates with severe asphyxia admitted to 20 tertiary hospitals in Henan Province between January 2022 and December 2025 were retrospectively enrolled and divided into a death group (n=267) and a survival group (n=569) according to outcome. Birth characteristics, resuscitation measures, and early complications were analyzed. Multivariable logistic regression was used to identify risk factors, and a nomogram prediction model was developed. Receiver operating characteristic curves, calibration curves, and decision curve analysis were used to evaluate the model's discrimination, calibration accuracy, and clinical applicability.