Frontiers in nutrition
Influence of Curcuma longa extract on cognitive function in mild cognitive impairment due to Alzheimer's disease: a single-arm, open-label, observational study
By Manabe Y.
Abstract
Objectives
Curcuma longa, commonly known as turmeric, is a dietary spice with potential biological effects. This study evaluated the association between intake of C. longa extracts (CLE) and cognitive function in individuals with mild cognitive impairment (MCI) due to Alzheimer's disease (AD).
Methods
This was a 4-month, single-arm, open-label, observational study of participants with MCI due to AD who were awaiting anti-amyloid therapy. Participants (n = 13) consumed the test food containing CLE, which includes the compounds bisacurone and turmeronols. Cognitive function was assessed at baseline and after 4 months using various cognitive assessments.