Brain and behavior
Blood Flow Restriction Training in Stroke Rehabilitation: A Narrative Review of Current Evidence and Future Directions
By Tong J, Song L, Jin J and 6 others.
Abstract
Background
Post-stroke motor deficits cause disability, while paresis and comorbidities may limit high-intensity training. Blood flow restriction training (BFRT) combines low-intensity exercise with partial vascular occlusion and may promote neuromuscular adaptations at low loads.
Methods
This narrative review synthesized peer-reviewed evidence on BFRT in stroke rehabilitation. Stroke-specific clinical studies, particularly randomized controlled trials (RCTs), were prioritized for evaluating clinical effects; experimental, preclinical, physiological, mechanistic, review, and guideline evidence provided context. RCT data included participant characteristics, protocols, outcomes, and adverse events. Two reviewers independently assessed risk of bias using the Cochrane Risk of Bias tool (RoB 1). Findings were synthesized qualitatively without meta-analysis or GRADE assessment.