Central European journal of public health
Paracetamol overdose: systematic review of case reports and national toxicological data (2018-2023)
By Mlíchová J, Šimandl O, Kotíková K and 4 others.
Abstract
Objectives
Paracetamol is widely used as an analgesic and antipyretic, but its accessibility also makes it a frequent drug in overdose cases. Increasing rates of intentional paracetamol poisoning, particularly among adolescents, raise public health concerns. This study aimed to examine recent patterns of paracetamol overdose and identify risk groups for intentional self-poisoning.
Methods
A systematic review of published case reports (2018-2023) describing paracetamol overdose was conducted using PubMed, Scopus, Web of Science, and the Cochrane Library. Additionally, a retrospective analysis of telephone inquiries to the Czech Toxicological Information Centre (TIC) during the same period was performed.