Brain and behavior
BRS-Assessed Resilience, Symptom Burden, and Functional Burden in Adolescents With Depressive, Anxiety, or Somatic Symptom-Related Disorders: A Single-Center Real-World Cross-Sectional Study
By Zhang L, Zhang M, Liu X and 3 others.
Abstract
Background
Adolescents with depressive, anxiety, and somatic symptom-related disorders often present with overlapping symptom domains and functional difficulties, but cross-sectional associations of Brief Resilience Scale (BRS) score with multidimensional symptom and functional burden in routine outpatient care remain insufficiently characterized.
Methods
This single-center, real-world, cross-sectional study retrospectively analyzed routinely collected data from adolescents aged 12-18 years attending a psychological/psychiatric outpatient clinic between January 2024 and December 2025. Eligible patients had clinician-recorded depressive, anxiety, or somatic symptom-related disorders and completed the BRS, PHQ-9, GAD-7, and PHQ-15. Associations of BRS score with symptom outcomes and predefined pragmatic functional-burden indicators were assessed using multivariable linear, logistic, and negative binomial regression models; restricted cubic spline analyses were exploratory.