Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
Effect of a Computer-Aided Device on Endoscopists' Biopsy Practice for Gastric Neoplasms: A Secondary Analysis of a Randomized Controlled Trial
By Du H, Tan S, Zeng Z and 7 others.
Abstract
Background
Endoscopic biopsy is fundamental for diagnosing gastrointestinal lesions, yet the effectiveness of AI assistance on endoscopists' biopsy strategies and efficiency for detecting gastric neoplasms remains unclear. This study aims to investigate this effectiveness.
Methods
This study is a secondary analysis of a randomized controlled trial (AI group: n = 13,440; control: n = 12,561) compared AI-assisted versus standard screening. The AI system marked high-risk and low-risk lesions with red and blue boxes, respectively. The AI group was stratified into red-box and non-red-box subgroups. Outcomes included neoplasm biopsy efficiency and proportion of non-biopsied documented lesions. The patient-level correlation between false-positive alerts and biopsy counts was examined. All analyses were based on the pathological results after centralized pathology review.