Brain and behavior
Prevalence and Predictors of Depressive Symptom Trajectories in Older Adults: A Systematic Review
By Li Y, Liu Q and Dong X.
Abstract
Purpose
To describe the distribution patterns and cross-study heterogeneity of depressive symptom trajectories in older adults and to identify consistent predictors of high-symptom trajectories for targeted intervention strategies.
Methods
Following PRISMA 2020 guidelines, six databases were searched from April 2010 to January 2026 for longitudinal studies using latent variable mixture models in adults aged ≥ 60 years. Study quality was assessed using the Newcastle-Ottawa Scale. Descriptive synthesis was employed due to methodological heterogeneity.