Journal of chemical health risks
Preformulation Development and Evaluation of a Herbal Extract-Based Ointment for Wound Healing”
By Khushbu Sahu.
Abstract
The present study aims to develop and evaluate a herbal wound healing ointment using medicinal plant extracts. Preformulation studies were performed to assess the compatibility and physicochemical properties of the ingredients. The prepared ointment was evaluated for parameters such as appearance, pH, homogeneity, spreadability, viscosity, extrudability, stability, and skin irritation. The formulation showed satisfactory physical characteristics and good stability, indicating its suitability as a topical wound care preparation. The study suggests that the herbal ointment has potential as a safe and effective alternative for wound healing, although further pharmacological and clinical studies are needed to confirm its efficacy.
Results
The herbal extracts had appropriate physical and chemical properties for the ointment preparation. The ointment had an acceptable appearance, smoothness, homogeneity, consistency, and spreadability. It can be said from the pH value of the f”rmul’ that there Is no chance of skin irritation because the pH was within the acceptable range. There was stability of the formula, as there was no change In its color, odor, consistency, and phase separation. Also, Evaluation of the formulation was carried out by measuring parameters such as pH and physical stability. centrifugation, spreadability, and extrudability, and all of them were satisfactory.



