Salmonella enterica-Associated Myopericarditis Following Acute Gastroenteritis

A previously healthy man in his early 20s presented with several days of febrile gastroenteritis, followed by acute pleuritic chest pain and dyspnea.Initial evaluation demonstrated markedly elevated cardiac biomarkers and inflammatory markers, electrocardiogram changes consistent with acute pericarditis, and preserved left ventricular systolic function on transthoracic echocardiogram.Stool polymerase chain reaction testing and blood cultures identified Salmonella enterica.A clinical diagnosis of suspected Salmonella-associated myopericarditis was made, although direct myocardial infection could not be confirmed.The patient was treated with targeted antimicrobial therapy in addition to anti-inflammatory therapy with aspirin and colchicine.His gastrointestinal and cardiac symptoms resolved rapidly, and he was discharged in stable condition with activity restriction and cardiology follow-up.This case highlights a rare but potentially life-threatening cardiac complication associated with non-typhoidal Salmonella infection in a young, otherwise healthy adult and underscores the importance of maintaining diagnostic vigilance when gastrointestinal prodromes precede acute chest pain with myocardial injury.