Spectrum of autonomic symptoms in seropositive and seronegative rheumatoid arthritis

More than 18 million people worldwide suffer from rheumatoid arthritis (RA), approximately 70% of whom are women [1]. Autonomic nervous system (ANS) involvement in RA significantly reduces patients' quality of life; however, its symptoms are often overlooked in the presence of articular manifestations. The influence of serological status on the spectrum of autonomic symptoms has not been sufficiently studied.