Zenodo
Is the evidence of clarithromycin causing QTc prolongation only theoretical?
By Tripdatabase.
Abstract
Evidence indicates that clarithromycin can cause QTc prolongation, with reported cases linking it to serious cardiac events. This suggests increased risk beyond purely theoretical bases, warranting cautious use, especially in patients with other QTc risk factors.
Keywords
- Cardiac electrophysiology and arrhythmias
- clarithromycin
- QTc prolongation
- drug-induced arrhythmia
- adverse cardiac events
- macrolide antibiotics
- drug safety
- Open access