Evaluation of Serum Acetylcholinesterase Levels and Sex Hormones (Estradiol and Progesterone) Among Postmenopausal Women and Assessment of Their Association with Clinical Characteristics

Abstract Background: Postmenopausal women experience a range of physiological and psychological changes associated with the cessation of ovarian and follicular activity, leading to decreased estrogen levels. This transition, typically occurring in the early 50s, is associated with various health challenges, including vasomotor symptoms, osteoporosis, and cardiovascular risks. Addressing these issues requires a comprehensive approach involving lifestyle modifications, medical interventions, and regular health screening to improve quality of life and manage symptoms effectively.

Methods

The study was conducted on 90 women aged 45–60 years who had experienced natural menopause, after obtaining written consent. Data were collected using a structured questionnaire and blood samples to measure estrogen and progesterone levels and acetylcholinesterase activity. Women with chronic illnesses or those regularly using hormone replacement therapy or antidepressants were excluded.