Advances in Clinical Medical Research
Exploring the role of serum magnesium in vascular calcification among chronic kidney disease patients undergoing hemodialysis
By Biswajit Mishra, Amruta Devi, Rama Shankar Rath and 2 others.
Abstract
Background
Chronic kidney disease (CKD) patients undergoing hemodialysis (HD) frequently develop vascular calcification, contributing to increased cardiovascular mortality. Magnesium (Mg), a crucial factor in mineral metabolism and vascular function, may influence the progression of carotid artery atherosclerotic calcification (CAAC). The objective is to evaluate the association between serum magnesium levels and carotid artery atherosclerotic calcification, as assessed by carotid intima-media thickness (CIMT), in patients with CKD receiving maintenance HD. Materials and Methods: This prospective, cross-sectional comparative study included 82 CKD patients on maintenance HD. Serum Mg levels were measured, and carotid intima-media thickness (CIMT) was assessed via ultrasound to determine CAAC presence. Various clinical, biochemical, and demographic factors were analyzed.