Société Internationale d’Urologie Journal
Is Addition of Ureteric Cutting Balloon Prior to Dilatation of Benign Ureteric Strictures with Paclitaxel-Coated Balloon Feasible? A Single-Centre Experience
By Jack Clarke, Aleksandr Pecherkin, Jack Karagiannakis and 3 others.
Abstract
Background/Objectives: Benign ureteric strictures most commonly arise iatrogenically after procedures such as ureteroscopy or uretero-ileal anastomosis. Whilst surgical reconstruction is gold-standard, endoluminal treatment is recommended for short strictures and is an excellent option for unsuitable, comorbid, previously operated or irradiated patients. Failure rates are higher than surgical management, however. Paclitaxel-coated balloons (PCBs) for endoluminal management have been shown to inhibit smooth muscle-cell proliferation and improve re-stenosis rates. In vascular stenosis, cutting-balloon pre-dilatation before PCB dilatation is used to give more-controlled dilatation and deeper drug penetration, with fewer complications and recurrences.



