The Effects of Multi-Strain Probiotic SLAB51 Intake on Aerobic Performance and Oxidative Stress Responses in Elite Athletes: A Randomized Crossover Trial

Background/Objectives: Exercise performance and recovery depend on interactions between energy metabolism and redox regulation. SLAB51, a multi-strain probiotic, may influence oxygen-related metabolism and antioxidant responses, but evidence in elite athletes remains limited. This study aimed to evaluate the effects of SLAB51 supplementation on aerobic exercise capacity and oxidative stress responses in elite athletes.

Methods

This randomized, double-blind, placebo-controlled crossover trial evaluated the effects of SLAB51 supplementation on aerobic exercise performance and oxidative stress in elite athletes. Participants received SLAB51 and placebo for one week each, separated by a two-week washout period. Assessments were performed at baseline, after a single intake, and after one week of intake. Exercise performance was evaluated using a treadmill-based Bruce protocol, and physiological and oxidative stress markers were measured. Data were analyzed using two-way repeated-measures analysis of variance (ANOVA), supplemented by post hoc linear mixed-effects models (LMMs) accounting for the crossover design.