Journal of Personalized Medicine
The Nuances of Cost-Related Medication Non-Adherence in Patients Receiving Immunosuppression Compared to Patients with Chronic Disease: A Cross-Sectional Study
By Samuel D. Good, Bryant R. England and Elizabeth R. Volkmann.
Abstract
Background
Medication adherence rates across diseases that require immunosuppression, including autoimmune diseases, are low. While cost barriers affect medication adherence, it is unknown whether adherence rates related to cost barriers differ between medically immunosuppressed patients and similar patients with other chronic diseases. The purpose of this study is to evaluate the influence of immunosuppression on cost-related medication non-adherence (CRMNA).
Methods
We performed a cross-sectional study utilizing the National Health Interview Survey (NHIS). Multivariable logistic regression was used to evaluate the association between immunosuppression and CRMNA, accounting for sex, age, education, race, income, life satisfaction, insurance status and marital status. Predicted probabilities of CRMNA were estimated by age group, and a subgroup analysis was performed among people who described as having poor health.