Journal of Functional Morphology and Kinesiology
Resistance Training Improves Respiratory Muscle Strength and Immune Response in Older Adults: A Randomized Clinical Trial
By N. Silva, Meiry De Souza Moura Maia, Anamei Silva-Reis and 12 others.
Abstract
Background
Aging is associated with sarcopenia, chronic low-grade inflammation, impaired functional capacity, and reduced respiratory muscle strength. Resistance training is recognized as an effective intervention to attenuate these age-related alterations; however, its effects on respiratory function and anti-aging biomarkers such as Klotho remain incompletely understood.
Methods
In this randomized controlled trial, 60 community-dwelling older adults (60–75 years) were randomly allocated to a control group (n = 30) or a resistance training group (n = 30). Participants in the intervention group completed a supervised 12-week resistance training program (three sessions/week). Assessments performed before and after the intervention included anthropometry, body composition, respiratory muscle strength (maximal inspiratory and expiratory pressures), handgrip strength, 1 min sit-to-stand test, oxygen saturation, plasma levels of IL-6, IL-10, TNF-α, Klotho, and hematological parameters.