Journal of Clinical Medicine
Serum Troponin and Procedural Duration Predict Delayed iASD Closure After Left Atrial Arrhythmia Ablation
By Ameen Abdulhasan Al-Alwany, Umniah Khajori, Mustafa Majid and 2 others.
Abstract
Background
Transseptal puncture is routinely performed to access the left atrium during catheter ablation of left atrial tachyarrhythmias. Although iatrogenic atrial septal defects (iASDs) frequently occur after the procedure, factors influencing delayed defect closure remain incompletely understood. Myocardial injury induced by radiofrequency (RF) ablation results in the release of cardiac troponin into the circulation and may reflect the extent of procedural tissue injury.
Methods
This prospective study included patients who underwent RF ablation for left atrial arrhythmias at the Iraqi Center for Heart Diseases in collaboration with the College of medicine, University of Baghdad between March 2023 and April 2024. Serum troponin concentrations, procedural duration, and echocardiographic assessment of iASD size were evaluated prospectively to determine their association with delayed atrial septal defect closure over a period of 3–6 months.