Journal of Clinical Medicine
Association of Platelet–Albumin–Bilirubin and Albumin–Bilirubin Scores with Angiographic No-Reflow in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary PCI
By Bülent Özlek, Veysel Ozan Tanık, Alperen Taş and 7 others.
Abstract
Background
The platelet–albumin–bilirubin (PALBI) and albumin–bilirubin (ALBI) scores integrate routinely available laboratory parameters with potential relevance to microvascular injury. We investigated their associations with angiographic no-reflow and incremental predictive value in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).
Methods
This retrospective, single-center study included 1539 consecutive patients with STEMI undergoing primary PCI. No-reflow was defined by final TIMI flow < 3 and/or myocardial blush grade 0–1 in the absence of a mechanical cause. Associations of PALBI and ALBI with no-reflow were assessed using multivariable logistic regression. Discrimination, calibration, reclassification, internal bootstrap validation, and restricted cubic spline analyses were performed.