Journal of Clinical Medicine
Contemporary Endovascular Treatment of Femoropopliteal Disease: Lesion Preparation, Antiproliferative Therapies, and Emerging Technologies
By Ma Lourdes del Río Solá, Sandra Pérez Fernández and Sergio Asensio Rodríguez.
Abstract
Background
Endovascular treatment of femoropopliteal atherosclerotic disease has evolved from plain balloon angioplasty and routine stenting toward lesion-oriented strategies that combine plaque assessment, selective vessel preparation, antiproliferative drug delivery, and provisional scaffolding. The increasing availability of drug-coated balloons, drug-eluting stents, atherectomy, intravascular lithotripsy, intravascular imaging, and sirolimus-based technologies has improved therapeutic options but has also made device selection more complex.
Objective
To synthesize comparative evidence and present a practical lesion-oriented framework for selecting vessel preparation, antiproliferative therapy, and selective scaffolding.



