Journal of Cardiovascular Development and Disease
The Association Between Relative Fat Mass and Estimated Glomerular Filtration Rate in a Community-Dwelling Hypertensive Population
By Shu Xie, Jiaying Ling, Qing Zhang and 4 others.
Abstract
Background
Obese individuals are at elevated risk of chronic kidney disease (CKD), particularly in the presence of comorbid hypertension, but whether relative fat mass (RFM) can serve as an indicator of early renal dysfunction in hypertensive populations remains unclear. Among community-dwelling adults with hypertension in Jiangsu Province, China, we evaluated the relationship between RFM and estimated glomerular filtration rate (eGFR).
Methods
We recruited 4439 adults with hypertension and defined reduced eGFR as <60 mL/min/1.73 m2. Multivariable logistic regression, subgroup analyses, restricted cubic spline (RCS) modeling, and receiver operating characteristic (ROC) curve analysis were used.