International Journal of Environmental Research and Public Health
Prevalence and Epidemiological Profile of VDRL Seroreactivity Among Blood Donations in the Brazilian Amazon
By Francisco Ocian de Araújo, Márcia Helena Machado Nascimento, Renata Bezerra Hermes de Castro and 11 others.
Abstract
Background
Reactive syphilis screening makes a donor ineligible and sends the associated components to discard. This study estimated the donation-level prevalence of VDRL seroreactivity and its sociodemographic, temporal and geographic distribution in six municipalities served by a regional blood center in Pará, Brazil, 2017–2023.
Methods
Census-based retrospective analysis of 362,705 donations recorded in the SBS.Web system of the Pará State Hemotherapy and Hematology Foundation. The donation was the unit of analysis; records could not be deduplicated by donor. Confirmatory treponemal results were unavailable, so active, treated and false-positive reactions could not be distinguished.