Diagnostics
Which Clinical, Radiological, Inflammatory, and Lesion-Related Characteristics Are Associated with Early Neurological Decompensation After Intracranial Mass Lesion Surgery?
By Fatma Betul Saylak and Burak Bahadır.
Abstract
Background
Early neurological decompensation is a clinically relevant concern following intracranial surgery, but factors associated with this early outcome remain incompletely characterized. This study evaluated factors associated with neurological decompensation within 48 h after surgery.
Methods
This retrospective, single-center study included 301 surgical episodes involving intracranial mass lesions. Early neurological decompensation was defined as a ≥2-point decrease in Glasgow Coma Scale (GCS) score, the development of a new neurological deficit, or the objective worsening of a pre-existing deficit within 48 h. Clinical, radiological, lesion-related, and hematological factors were evaluated using logistic regression and ROC analyses, with bootstrap internal validation.