International Journal of Science and Research
Nickel Sensitization in Patients with Hand Eczema: A Cross-Sectional Study from Northeast India
By Drisya Payyormmel and Ninganna Shivaraya.
Abstract
Background
Nickel is one of the commonest causes of allergic contact sensitization and remains an important trigger of hand eczema. Exposure to jewellery, piercings and other metal-containing consumer products makes nickel particularly relevant in younger individuals.
Objectives
To describe the pattern of nickel sensitization among patients with hand eczema, with particular emphasis on age, sex and clinical phenotype.
Methods
This cross-sectional study included 126 consecutive patients with hand eczema attending a tertiary care centre between February 2023 and January 2025. Patch testing was performed using the Indian Standard Series, with readings at 48 and 96 hours according to International Contact Dermatitis Research Group criteria.