European Journal of Case Reports in Internal Medicine
Against all odds: repeated successful pregnancies in two women with unrepaired single-ventricle physiology
By Madina Sugralimova, Karlygash Togyzbayeva, Murat Mukarov and 2 others.
Abstract
Introduction
Pregnancy in women with unrepaired single-ventricle physiology is rare and associated with substantial maternal and foetal risk. Evidence regarding pregnancy outcomes in this population remains limited.
Case description
We report three successful pregnancies in two women with unrepaired double-inlet left ventricle, transposition of the great arteries and valvular/sub-valvular pulmonary stenosis. Both women were classified as modified World Health Organization class IV and received multidisciplinary care throughout pregnancy. Despite complex congenital heart disease, systemic ventricular function and oxygen saturation remained stable. All three pregnancies resulted in live births. However, foetal growth restriction, oligohydramnios, placental insufficiency, prematurity and prolonged neonatal hospitalisation occurred in all pregnancies. One patient successfully completed two consecutive pregnancies without maternal cardiovascular deterioration.