European Journal of Case Reports in Internal Medicine
Ulcerative pancreatic panniculitis complicated by secondary infection and delayed wound healing in a patient undergoing haemodialysis
By 浩大 中原, Mitsumasa Okano, Ryusuke Ono and 4 others.
Abstract
Introduction
Pancreatic panniculitis is a rare cutaneous manifestation of pancreatic disease.
Case description
A 75-year-old man on maintenance haemodialysis with a history of IgG4-related autoimmune pancreatitis presented with painful subcutaneous nodules on the lower extremities and a purulent leg ulcer. Elevated pancreatic enzyme levels and imaging findings suggested an exacerbation of chronic pancreatitis. Histopathological examination of a skin biopsy revealed lobular panniculitis with fat necrosis and ghost-like adipocytes, confirming the diagnosis of pancreatic panniculitis. Subcutaneous nodules regressed with conservative treatment for pancreatitis; however, the ulcer became secondarily infected and showed delayed wound healing.