Heterogeneous Renal Response to Therapy in Type 2 Diabetes: Albuminuria Categories

Background

The comparative effectiveness of renin-angiotensin system (RAS) blockade and sodium-glucose cotransporter 2(SGLT2) inhibitors across different stages of albuminuria remain incompletely characterized despite demonstrating renoprotective association in randomized trials. This study evaluates the association between angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB), SGLT2 inhibitor, and their combination across baseline albuminuria strata.

Methods