Squamous Cell Carcinoma in the Diabetic Foot: A Review of Published Case Reports

Introduction

Squamous cell carcinoma (SCC) is a malignant tumour arising from epidermal keratinocytes and is the second most common form of skin cancer globally. Although relatively rare on the foot, SCC and its variants may occur in people with diabetes and can mimic common diabetes-related foot ulcerations. This diagnostic overlap presents a risk of delayed recognition and treatment. The aim of this review was to synthesise published case reports of SCC occurring in the diabetic foot and to describe patient characteristics, clinical presentation, and outcomes.